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Ovulation Pain & Endometriosis: Understanding Causes, Symptoms & Treatment

Key Facts

  • Endometriosis can cause severe ovulation pain due to tissue growth outside the uterus, leading to symptoms like cramping and gastrointestinal issues.
  • Identifying ovulation pain linked to endometriosis involves recognizing persistent pelvic pain, abnormal bleeding, and gastrointestinal symptoms.
  • Consult a healthcare professional for accurate diagnosis and treatment options, including hormonal contraceptives and self-care strategies like heat application.

While ovulation pain is a common experience, sometimes this pain can be a sign of an underlying medical condition, such as endometriosis. This comprehensive article will delve into the intricate relationship between ovulation pain and endometriosis. We will discuss:

  • The reasons why endometriosis can cause ovulation pain.
  • How does his pain differentiate from regular ovulation discomfort?
  • Practical advice on how to manage endometriosis-related ovulation pain.

We aim to provide you with a deeper understanding of ovulation pain and its potential link to endometriosis, empowering you to take control of your reproductive health. With one in five women reporting discomfort during ovulation, it’s important to understand what it means for your body and when treatment may be necessary.

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Can endometriosis make ovulation painful?

What is Endometriosis?

Endometriosis is a medical condition that causes tissue similar to the uterus lining to grow on other anatomic structures. It is often located in the ovaries , fallopian tubes, and uterus (womb). Endometriosis is one of women’s most common causes of pelvic pain and infertility. Endometriosis affects one in nine Australian women . However, not all women with endometriosis have debilitating pain; some may not even realise they have it. Pain caused by endometriosis often increases during menstruation, though sometimes it can be present at other times in the month. It can also occur with symptoms like constipation, diarrhoea, nausea, and vomiting.

Can Endometriosis Cause Ovulation Pain?

If endometriosis involves the ovaries, it has the potential to cause agonising pain as you ovulate each month. The symptoms of ovulation pain are severe cramping or pelvic pain that typically begins in the lower abdomen and slowly spreads to the back and thighs. The ovaries are the female reproductive organs that produce eggs through ovulation. Ovulation pain occurs in many women due to high oestrogen levels and is caused by the uterus’s endometrial tissue breakdown. If this tissue is left behind in the ovaries, it can cause a condition called adhesions that attach various organs.

Ovarian cysts form when endometrial cells stick to the ovary, collecting blood and debris. During each ovulation cycle, these cysts undergo stress or minor ruptures that release their contents into nearby tissues. This triggers inflammation, making nerve fibres more sensitive and increasing ovulation-related pain.

An ovulation predictor kit measures luteinising hormone (LH) levels in your urine. A rise in LH—typically 24 to 36 hours before ovulation—indicates the start of your fertile window. This accurate signal allows you to determine whether your pelvic discomfort coincides with the natural LH surge or if further evaluation is needed, especially when distinguishing normal ovulation pain from pain associated with conditions like endometriosis.

Image courtesy of The Bright Girl Guide by Demi Spaccavento. What is the best treatment for ovulation pain?

How to Know if Your Ovulation Pain Is Due to Endometriosis

Understanding whether your ovulation pain is due to endometriosis can be a complex process. However, certain symptoms can help differentiate endometriosis-related pain from other types of discomfort. These include:

Persistent Pelvic Pain

If you experience pain in your pelvis lasting more than two days, it is advisable to seek medical attention. This persistent discomfort could be a sign of this condition.

Pain Accompanied by Gastrointestinal Symptoms

Endo can sometimes cause symptoms such as vomiting or diarrhea. If these symptoms accompany your ovulation pain, it may be due to endometriosis.

Abnormal Bleeding

Experiencing abnormal bleeding around the time of ovulation is a common symptom of endometriosis. If you notice this symptom, it could be an indication of endometriosis.

Period-Related Debilitation

Another sign can be if your symptoms are mild but become debilitating at the onset of each menstrual period.

Pain During Urination

Endometriosis can cause pain in your bladder or pelvis during urination. If you experience this type of discomfort, it may be due to endometriosis.

Chronic Fatigue

Endometriosis can lead to chronic fatigue. Constant fatigue could be a symptom of this condition.

Gastrointestinal Discomfort

Endometriosis can cause constipation, diarrhoea, and shooting rectal pain. If you experience these symptoms, particularly in conjunction with ovulation pain, it could be a sign of endometriosis. These symptoms can provide valuable clues about whether your ovulation pain is due to endometriosis. However, it’s important to consult with a healthcare professional for a definitive diagnosis and appropriate treatment.

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Endometriosis-Related Ovulation Pain

How Hormonal Changes Affect Ovulation Pain

Ovulation happens when hormones signal the release of an egg. For women with endometriosis, these hormones can trigger unexpected reactions in cells outside the uterus. This can lead to increased pain during the middle of the menstrual cycle.

  • Hormone Surge – Mid-cycle hormone levels rise to initiate ovulation.
  • Unusual Cell Response – Cells outside the uterus react differently, heightening sensitivity.
  • Tissue Adaptation – Repeated cycles cause gradual changes in surrounding tissues, intensifying discomfort.

Understanding this progression underscores the importance of seeking personalised medical advice, as tailored treatment is crucial for managing ovulation pain in endometriosis.

Endometriomas are cysts caused by endometriosis. When these cysts become large, they may rupture, releasing menstrual blood into the abdominal cavity. This event can cause severe pain, particularly noticeable during ovulation.

What Are The Stages of Endometriosis?

Endometriosis is classified into four stages based on the size, depth, and spread of lesions and adhesions, according to the Royal Australian and New Zealand College of Obstetricians and Gynaecologists (RANZCOG). This staging system focuses on anatomical factors and does not always match the level of pain experienced.

Pain responses in endometriosis vary widely. Some women with minimal lesions may have significant pelvic discomfort, while others with extensive tissue involvement might experience only mild symptoms. This variation is due to differences in nerve sensitivity, local inflammatory responses, and hormonal influences.

Stage 1 (Minimal Endometriosis)

  • Features small, isolated implants with few or no adhesions.
  • Often presents with subtle or no symptoms, though some may experience mild pelvic discomfort.

Stage 2 (Mild Endometriosis)

  • Involves slightly larger lesions and limited scar tissue.
  • Symptoms are usually mild, and the extent of tissue involvement doesn’t always correlate with pain levels.

Stage 3 (Moderate Endometriosis)

  • Characterised by more numerous and larger lesions, possible ovarian cysts (endometriomas), and some adhesions.
  • Pain levels can vary; moderate anatomical changes do not necessarily mean severe pain for every patient.

Stage 4 (Severe Endometriosis)

  • Defined by widespread, deep lesions and extensive adhesions.
  • Despite the advanced stage, many women report mild to moderate pain, indicating that nerve sensitivity and inflammatory responses significantly influence symptom severity.

Recognising that the clinical stage is not a definitive measure of pain intensity helps set realistic expectations and supports a personalised approach to treatment and management.

For example, endometriosis may stay the same over time for a woman if her symptoms are mild enough and she has a low level of pelvic inflammation or other factors.

Could My Pain be From Normal Ovulation?

Because pain is relative, not all pain during ovulation is considered abnormal. Some women experience mild pain as a normal indication that ovulation has occurred. The following signs can pinpoint normal ovulation pain :

Location

The discomfort is typically felt in the lower abdomen, just above the hip bone. It’s usually localised and can be traced to the side of the body where the ovary has released an egg during that particular menstrual cycle .

Timing

Normal ovulation pain often occurs around two weeks before the onset of the next menstrual period, coinciding with the ovulatory menstrual stage .

Duration

The pain associated with normal ovulation can last anywhere from a few minutes to 48 hours. However, it typically doesn’t persist beyond this timeframe.

Intensity

Normal ovulation pain is usually mild and does not cause additional symptoms like nausea. It’s a discomfort that’s noticeable but not debilitating.

When to Seek Professional Help

If you’re experiencing ovulation pain that you believe may be linked to endometriosis, it’s crucial to consult with a healthcare professional, preferably a gynaecologist. They can thoroughly evaluate your symptoms and provide an informed opinion on whether endometriosis could be a potential cause. However, the definitive diagnosis of endometriosis can only be confirmed through a minimally invasive surgery known as a laparoscopy . This procedure allows for the diagnosis of endometriosis and provides an opportunity for immediate treatment.

Endometriosis & Support

Medical Management Using Hormonal Contraceptives

Hormonal treatments, such as combined oral contraceptives and progestin-only options, are key in managing endometriosis-related ovulation pain. These medications primarily suppress ovulation, preventing egg release and stabilising hormone levels, especially oestrogen. Lower oestrogen limits the cyclical growth and breakdown of endometrial-like tissue outside the uterus, reducing inflammation and easing ovulation pain.

Besides reducing oestrogen-driven inflammation, hormonal contraceptives decrease prostaglandin production—compounds that cause pain and tissue irritation. This lowers discomfort and may prevent scar tissue and adhesions in the pelvic area.

Hormonal contraceptives, like all treatments, have potential side effects. Some women may experience breakthrough bleeding, mood changes, weight fluctuations, or breast tenderness. There is also a risk of blood clots, especially for those with certain risk factors. These risks emphasise the need for personalised treatment plans and regular consultation with a healthcare professional.

Consulting a qualified gynaecologist ensures the benefits of these treatments are weighed against potential side effects and that the regimen suits your individual health needs. Regular follow-ups and open communication with your doctor are essential to optimise treatment efficacy and safety.

In addition to medical treatments, several self-care strategies can be employed at home to help manage the symptoms of endometriosis. These include:

Applying Heat

A heating pad, self-heating patches, or a hot water bottle can help soothe the pain. Immersing yourself in a warm bath can also provide relief.

Utilising Natural Remedies

Warm baths infused with Epsom salts or essential oils such as lavender and chamomile can offer a natural approach to pain relief.

Using a TENS Machine

Transcutaneous Electrical Nerve Stimulation (TENS) machines send electrical impulses to the nerves, which can help block the transmission of pain signals to the brain, relieving endometriosis-associated discomfort. Remember, it’s essential to consult with a healthcare professional before starting any new treatment regimen, including natural remedies and TENS therapy. When a medical issue arises , seeking professional help is vital. If you suspect endometriosis, your doctor may request that you see a specialist .

Impact on Fertility

Endometriosis can reduce fertility through physical and hormonal factors. Adhesions from endometrial implants can tether or block the ovaries and fallopian tubes, preventing eggs from traveling to the uterus. Hormonal imbalances can disrupt ovulation and make the uterine lining less receptive, hindering implantation.

  • Adhesions and Blockages: Scar tissue can block fallopian tubes, reducing the chance of eggs meeting sperm and lowering fertility.
  • Hormonal Disruptions: Hormone changes can affect ovulation timing and endometrial quality, both vital for conception.

Early diagnosis and conversations with healthcare providers, including local fertility specialists in Australia, are crucial for managing these challenges. Evidence-based treatments—from hormone regulation to minimally invasive surgery—can preserve reproductive health and improve outcomes for women with endometriosis.

Empowering Your Fertility Journey with Fertility2Family

At Fertility2Family, we understand the complexities of fertility issues like endometriosis. Our blog provides in-depth, reliable information to help you navigate these challenges. If you’re experiencing ovulation pain and suspect endometriosis, our affordable ovulation tests and fertility kits can be valuable tools in your journey. Fertility2Family is your partner in understanding and managing your fertility health. For more information, get in touch with us today.

Sources:
Fertility2Family only uses trusted & peer-reviewed sources to ensure our articles’ information is accurate and reliable.

Ades, A. (2021) Endometriosis stages” stages I – IV explained, Advanced Gynaecology Melbourne Australia. Available at: https://www.advancedgynaecologymelbourne.com.au/endometriosis/stages (Accessed: 01 September 2023). Endometriosis Australia (2023) Research , Endometriosis Australia . Available at: https://endometriosisaustralia.org/research/ (Accessed: 22 October 2023). Brott, N.R. and Le, J.K. (2023) Mittelschmerz – StatPearls – NCBI Bookshelf, Available at: https://www.ncbi.nlm.nih.gov/books/NBK549822/ (Accessed: 01 September 2023). Christiano, D. (2019) What are chocolate cysts?, Healthline. Available at: https://www.healthline.com/health/womens-health/chocolate-cyst (Accessed: 01 September 2023). Cleveland Clinic (2023) Transcutaneous electrical nerve stimulation (TENS), Cleveland Clinic. Available at: https://my.clevelandclinic.org/health/treatments/15840-transcutaneous-electrical-nerve-stimulation-tens (Accessed: 01 September 2023). Cleveland Clinic (2022) Hydrosalpinx: Causes, symptoms, diagnosis & treatment, Cleveland Clinic. Available at: https://my.clevelandclinic.org/health/diseases/24437-hydrosalpinx (Accessed: 01 September 2023). Department of Health & Human Services (2003) Ovulation pain, Better Health Channel Australia. Available at: https://www.betterhealth.vic.gov.au/health/conditionsandtreatments/ovulation-pain (Accessed: 01 September 2023). Healthdirect Australia (2023) Endometriosis , healthdirect . Available at: https://www.healthdirect.gov.au/endometriosis (Accessed: 22 October 2023). Giorgi, A. (2022). Laparoscopy: Purpose, preparation, procedure, and recovery, Healthline. Available at: https://www.healthline.com/health/laparoscopy (Accessed: 01 September 2023). Ovaries (2023) Hormones Australia. Available at: https://www.hormones-australia.org.au/the-endocrine-system/ovaries/ (Accessed: 01 September 2023). The Royal Women’s Hospital (2015) Choosing not to treat endometriosis, The Royal Women’s Hospital Australia. Available at: https://www.thewomens.org.au/health-information/periods/endometriosis/treating-endometriosis (Accessed: 01 September 2023). Todd, N. (2023) Endometrial cysts: Symptoms, diagnosis, treatment, WebMD. Available at: https://www.webmd.com/women/endometriosis/endometrial-cysts (Accessed: 01 September 2023).

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Evan Kurzyp

Evan is the founder of Fertility2Family and is passionate about fertility education & providing affordable products to help people in their fertility journey. Evan is a qualified Registered Nurse and has expertise in guiding & managing patients through their fertility journeys.

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